This condition is uncommon but can occur in puppies between 1 and 4 months of age. The cause is unknown but may be immune-mediated. The face of these pups will initially swell and be confused with angioedema. Clinical signs include swelling of lymph nodes under the jaw and papules and pustules (lumps, some of which may ooze pus) on the nose, lips, face, and around the eyes. Hair may be lost from these areas and draining exudates will ooze from the skin. The ears may become heavily involved and many pups have a fever and loose their appetite. Diagnosis is based on physical exam, cytologic exam of exudates (while there will be pus, this is not an infection), cultures and skin biopsy. These dogs really look bad but can be treated well in most cases. ((Juvenile Cellulitis))

If treatment is not undertaken early, severe scaring of the skin will occur. Large doses of prednisolone or dexamethasone for 2-4 weeks will work well. Antibiotics are often used although infection is the exception not the rule. Cleansing soaks or shampoos can also be beneficial, as can topical antibiotic/steroid solutions to help remove crusts and debris from the skin surface.

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